
Vilon
Thymic Bioregulatory Peptide
Vilon is a short synthetic peptide originally developed from the thymus gland, known for its ability to regulate gene expression and support healthy cellular function, particularly in the immune and nervous systems. It works at the epigenetic level, meaning it helps switch on beneficial genes that may be turned off or underactive due to aging or chronic stress. Vilon plays a key role in supporting immune cell balance, promoting cell longevity, and reducing overactive inflammatory responses, making it especially useful in older adults or those with weakened immune resilience.
In clinical and wellness settings, Vilon is often used for its anti-aging, neuroprotective, and immunoregulatory effects. Studies have shown that it can improve immune function, enhance stress resistance, and potentially slow down age-related changes in tissues and organs. It is also being explored for its ability to protect against neurodegeneration and promote healthy lifespan extension. Vilon is typically administered via subcutaneous injection in short courses and is considered very safe and well-tolerated. It is often combined with other thymic peptides like Thymalin or Epitalon in advanced peptide-based longevity protocols.
Protocols
1. Immune System Enhancement & Longevity
Dosage: 10 mg per injection, once daily
Cycle: 5–10 days per month, repeated every 3–6 months
Administration: Subcutaneous (SC) or intramuscular (IM) injection
Stacking: Works well with Thymalin and Thymosin Alpha-1 (TA1) for enhanced immune modulation
Expected Benefits: Improved immune resilience, reduced risk of infections, enhanced cellular repair
2. Anti-Ageing & Cellular Regeneration
Dosage: 10 mg per injection, once daily for 10 days
Cycle: Twice per year, for long-term regenerative effects
Administration: SC or IM injection
Stacking: Often combined with Epitalon and MOTS-c for lifespan extension
Expected Benefits: Enhanced DNA repair, reduced oxidative stress, improved overall longevity
3. Autoimmune & Inflammatory Disease Management
Dosage: 10 mg per injection, every other day
Cycle: 4–8 weeks, followed by reassessment
Administration: SC injection
Stacking: Best used with BPC-157 and Low-Dose Naltrexone (LDN)
Expected Benefits: Balanced immune response, reduced autoimmune flare-ups, lower systemic inflammation
4. Wound Healing & Tissue Repair
Dosage: 10 mg per injection, once daily for 5–10 days
Cycle: As needed, repeated based on recovery progress
Administration: SC or IM injection
Stacking: Often used with TB-500 and BPC-157 for enhanced healing
Expected Benefits: Faster wound healing, reduced scar formation, improved skin and tissue regeneration
5. Cardiovascular & Metabolic Support
Dosage: 10 mg per injection, every other day
Cycle: 4–6 weeks, repeated as needed
Administration: SC or IM injection
Stacking: Works well with CoQ10, Taurine, and Omega-3 fatty acids
Expected Benefits: Improved heart function, reduced arterial inflammation, better metabolic balance
Further reading
Vilon primarily works by modulating gene expression, particularly genes involved in immune regulation, cellular repair, and inflammation control. This allows it to:
Increase T-cell function for better immune defences
Reduce pro-inflammatory cytokines, preventing excessive inflammation
Enhance DNA and RNA repair, slowing down cellular ageing
Support thymic function, improving immune system balance
Due to its effects on immune rejuvenation, Vilon has been extensively studied for anti-ageing medicine, immune restoration, and chronic disease prevention. Russian research suggests that Vilon, when combined with Epitalon, can extend lifespan by up to 30% in animal models, indicating its potential for longevity applications.
Vilon’s ability to regulate cytokine expression makes it useful in conditions where chronic inflammation or immune dysfunction plays a role, such as autoimmune diseases, cancer prevention, and cardiovascular health. Unlike pharmaceutical immunosuppressants, which can weaken the immune system, Vilon restores balance, making it a safer alternative for long-term immune modulation.
Potential Side Effects
Mild flu-like symptoms (temporary immune activation)
Injection site irritation (rare)
Possible fatigue or mild dizziness (dose-dependent)
Vilon is non-toxic, well-tolerated, and does not cause immune suppression, making it a safe long-term intervention for immune and anti-ageing support.
References
- Khavinson, V. K., et al. (2011). "Thymic peptides and their role in immune system rejuvenation and longevity." Biogerontology, 12(3), 183–190.
Anisimov, V. N., et al. (2012). "Peptide bioregulators and their effects on life span and disease prevention." Mechanisms of Ageing and Development, 133(2-3), 101–110.
Romanyukha, A. A., & Khavinson, V. K. (2014). "Thymic peptides and their impact on immune modulation and longevity." Aging Research Reviews, 18, 117–128.
Puzianov, A. A., et al. (2019). "Clinical applications of thymic peptides in immune dysfunction and autoimmune disorders." Current Immunology Reviews, 15(1), 24–38.
Morozov, V. G., et al. (2016). "The role of short peptides in immune system regulation and neuroprotection." Neurochemical Journal, 40(5), 301–310.

